Embryonic stem cell-derived cardiomyocytes for the treatment of doxorubicin-induced cardiomyopathy

Embryonic stem cell-derived cardiomyocytes for the treatment of doxorubicin-induced cardiomyopathy

Abstract Background Doxorubicin (Dox) is a chemotherapy drug with limited application due to cardiotoxicity that may progress to heart failure. This study aims to evaluate the role of cardiomyocytes derived from mouse embryonic stem cells (CM-mESCs) in the treatment of Dox-induced cardiomyopathy (DI...

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Main Authors: Danúbia Silva dos Santos, Guilherme Visconde Brasil, Isalira Peroba Rezende Ramos, Fernanda Cristina Paccola Mesquita, Tais Hanae Kasai-Brunswick, Michelle Lopes Araújo Christie, Gustavo Monnerat Cahli, Raiana Andrade Quintanilha Barbosa, Sandro Torrentes da Cunha, Jonathas Xavier Pereira, Emiliano Medei, Antonio Carlos Campos de Carvalho, Adriana Bastos Carvalho, Regina Coeli dos Santos Goldenberg
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Stem Cell Research & Therapy
Subjects:
Dox-induced cardiomyopathy
Heart failure
Cardiomyocytes derived from mouse embryonic stem cells
Cell therapy
Online Access:http://link.springer.com/article/10.1186/s13287-018-0788-2

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http://link.springer.com/article/10.1186/s13287-018-0788-2

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