Thresholds of Endoglin Expression in Endothelial Cells Explains Vascular Etiology in Hereditary Hemorrhagic Telangiectasia Type 1

Thresholds of Endoglin Expression in Endothelial Cells Explains Vascular Etiology in Hereditary Hemorrhagic Telangiectasia Type 1

Hereditary Hemorrhagic Telangiectasia type 1 (HHT1) is an autosomal dominant inherited disease characterized by arteriovenous malformations and hemorrhage. HHT1 is caused by mutations in <i>ENDOGLIN</i>, which encodes an ancillary receptor for Transforming Growth Factor-β/Bone Morphogene...

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Bibliographic Details
Main Authors: Georgios Galaris, Kévin Montagne, Jérémy H. Thalgott, Geoffroy J. P. E. Goujon, Sander van den Driesche, Sabrina Martin, Hans-Jurgen J. Mager, Christine L. Mummery, Ton J. Rabelink, Franck Lebrin
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
endoglin
hereditary hemorrhagic telangiectasia
cell signaling
endothelial cells
Online Access:https://www.mdpi.com/1422-0067/22/16/8948

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https://www.mdpi.com/1422-0067/22/16/8948

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