The Secretome Derived From 3D-Cultured Umbilical Cord Tissue MSCs Counteracts Manifestations Typifying Rheumatoid Arthritis

The Secretome Derived From 3D-Cultured Umbilical Cord Tissue MSCs Counteracts Manifestations Typifying Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disorder whose treatment is mostly restricted to pain and symptom management and to the delay of joint destruction. Mesenchymal stem/stromal cells from the umbilical cord tissue (UC-MSCs) have previously been proven to be immunomodulatory and more efficient...

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Bibliographic Details
Main Authors: Joana P. Miranda, Sérgio P. Camões, Maria M. Gaspar, Joana S. Rodrigues, Manuela Carvalheiro, Rita N. Bárcia, Pedro Cruz, Helder Cruz, Sandra Simões, Jorge M. Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
mesenchymal stem/stromal cells
umbilical cord tissue
3D culture
secretome
arthritic signs
rheumatoid arthritis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00018/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00018/full

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