Host transcriptomic profiling of COVID-19 patients with mild, moderate, and severe clinical outcomes

Host transcriptomic profiling of COVID-19 patients with mild, moderate, and severe clinical outcomes

Characterizing key molecular and cellular pathways involved in COVID-19 is essential for disease prognosis and management. We perform shotgun transcriptome sequencing of human RNA obtained from nasopharyngeal swabs of patients with COVID-19, and identify a molecular signature associated with disease...

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Bibliographic Details
Main Authors: Ruchi Jain, Sathishkumar Ramaswamy, Divinlal Harilal, Mohammed Uddin, Tom Loney, Norbert Nowotny, Hanan Alsuwaidi, Rupa Varghese, Zulfa Deesi, Abdulmajeed Alkhajeh, Hamda Khansaheb, Alawi Alsheikh-Ali, Ahmad Abou Tayoun
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Transcriptome sequencing
COVID-19
Disease severity
Expression signature
Nasopharyngeal swabs
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020305419

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http://www.sciencedirect.com/science/article/pii/S2001037020305419

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