Challenges and Opportunities in NUT Carcinoma Research

NUT carcinoma (NC) is a type of aggressive cancer driven by chromosome translocations. Fusion genes between a DNA-binding protein, such as bromodomain and extraterminal domain (BET) proteins, and the testis-specific protein NUTM1 generated by these translocations drive the formation of NC. NC can de...

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Bibliographic Details
Main Authors: Maxwell C. Hakun, Bin Gu
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/2/235