Synthesis and Anti-Influenza Virus Activities of a Novel Class of Gastrodin Derivatives

A series of substituted aryl glycoside analogues of gastrodin have been identified as potential anti-influenza agents. The most potent inhibitor 1a exhibited moderate inhibitory activity against the A/Hanfang/359/95(H3N2) and A/FM/1/47(H1N1) strains of the influenza A virus (IC50 values of 44.40 and...

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Main Authors: Zhuo-Rong Li, Jian-Dong Jiang, Yu-Huan Li, Tian Zhang, Xing-Yue Ji, Bo Wang, Guang-Hui Zheng, Hui-Qiang Wang, Lin-Lin Ma, Wei-Ying He, Si-Tu Xue
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/4/3789