Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation

Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation

Methylmercury (MeHg) is a potent neurotoxin that affects particularly the developing brain. Since MeHg is a potent electrophilic agent, a wide range of intracellular effects occur in response to its exposure. Yet, the molecular mechanisms associated with MeHg-induced cell toxicity have yet to be ful...

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Bibliographic Details
Main Authors: Takamitsu Unoki, Masahiro Akiyama, Yoshito Kumagai, Filipe Marques Gonçalves, Marcelo Farina, João Batista Teixeira da Rocha, Michael Aschner
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Genetics
Subjects:
methylmercury
toxicity
Nrf2
gene expression
central nervous system
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00373/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00373/full

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