The olfactory epithelium as a port of entry in neonatal neurolisteriosis

Listeria monocytogenes causes meningitis in newborns. Here, Pägelow et al. present a mouse model of neonatal cerebral listeriosis, and show that nasal inoculation, but not intragastric administration, leads to early brain infection in the absence of bacteraemia during the neonatal period.

Bibliographic Details
Main Authors: Dennis Pägelow, Chintan Chhatbar, Andreas Beineke, Xiaokun Liu, Andreas Nerlich, Kira van Vorst, Manfred Rohde, Ulrich Kalinke, Reinhold Förster, Stephan Halle, Peter Valentin-Weigand, Mathias W. Hornef, Marcus Fulde
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06668-2