Evidence for a Common Genetic Origin of Classic and Milder Adult-Onset Forms of Isolated Hypogonadotropic Hypogonadism

Evidence for a Common Genetic Origin of Classic and Milder Adult-Onset Forms of Isolated Hypogonadotropic Hypogonadism

Multiple metabolic and inflammatory mechanisms are considered the determinants of acquired functional isolated hypogonadotropic hypogonadism (IHH) in males, whereas classic IHH is a rare congenital condition with a strong genetic background. Since we recently uncovered a frequent familiarity for cla...

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Bibliographic Details
Main Authors: Biagio Cangiano, Paolo Duminuco, Valeria Vezzoli, Fabiana Guizzardi, Iacopo Chiodini, Giovanni Corona, Mario Maggi, Luca Persani, Marco Bonomi
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Journal of Clinical Medicine
Subjects:
GnRH
Kallmann’s Syndrome
Late onset hypogonadism
obesity
IHH
testosterone cutoff
BMI
oligogenicity
Online Access:https://www.mdpi.com/2077-0383/8/1/126

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https://www.mdpi.com/2077-0383/8/1/126

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