Characterization of a B16-F10 melanoma model locally implanted into the ear pinnae of C57BL/6 mice.

The common experimental use of B16-F10 melanoma cells focuses on exploring their metastatic potential following intravenous injection into mice. In this study, B16-F10 cells are used to develop a primary tumor model by implanting them directly into the ears of C57BL/6J mice. The model represents a r...

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Bibliographic Details
Main Authors: Marine Potez, Verdiana Trappetti, Audrey Bouchet, Cristian Fernandez-Palomo, Esra Güç, Witold W Kilarski, Ruslan Hlushchuk, Jean Laissue, Valentin Djonov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6218054?pdf=render