Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines

Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines

<p>Abstract</p> <p>Background</p> <p>The zebrafish is recognized as a versatile cancer and drug screening model. However, it is not known whether the estrogen-responsive genes and signaling pathways that are involved in estrogen-dependent carcinogenesis and human cancer...

Full description

Bibliographic Details
Main Authors: Govindarajan Kunde R, Li Haixia, Murthy Karuturi RK, Fu Pan Y, Thomsen Jane S, Lin Chin Y, Lee Serene GP, Lam Siew, Nick Lin CH, Bourque Guillaume, Gong Zhiyuan, Lufkin Thomas, Liu Edison T, Mathavan Sinnakaruppan
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Medical Genomics
Subjects:
zebrafish
microarray
estrogen
anti-estrogen ICI 182,780
estrogen-responsive genes
signaling pathways
carcinogenesis
human cancer cell lines
molecular conservation
model organism
Online Access:http://www.biomedcentral.com/1755-8794/4/41

Internet

http://www.biomedcentral.com/1755-8794/4/41

Similar Items