Rapid Intervention of Chlorpromazine and Promethazine for Hibernation-Like Effect in Stroke: Rationale, Design, and Protocol for a Prospective Randomized Controlled Trial

Rapid Intervention of Chlorpromazine and Promethazine for Hibernation-Like Effect in Stroke: Rationale, Design, and Protocol for a Prospective Randomized Controlled Trial

Background: Following an acute ischemic stroke (AIS), rapidly initiated reperfusion therapies [i. e., intravenous thrombolysis (IVT) and endovascular treatment (EVT)] demonstrate robust clinical efficacy. However, only a subset of these patients can benefit from these therapies due to their short tr...

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Bibliographic Details
Main Authors: Shuyu Lv, Wenbo Zhao, Gary B. Rajah, Chaitu Dandu, Lipeng Cai, Zhe Cheng, Honglian Duan, Qingqing Dai, Xiaokun Geng, Yuchuan Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Neurology
Subjects:
acute ischemic stroke (AIS)
phenothiazine
neuroprotection
intravenous thrombolysis
rt-PA
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.621476/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.621476/full

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