Downregulation of miR-181b-5p Inhibits the Viability, Migration, and Glycolysis of Gallbladder Cancer by Upregulating PDHX Under Hypoxia

Downregulation of miR-181b-5p Inhibits the Viability, Migration, and Glycolysis of Gallbladder Cancer by Upregulating PDHX Under Hypoxia

BackgroundGallbladder cancer (GBC) is a malignant cancer with poor prognosis. Evidences have shown that miRNAs are closely related to the occurrence of GBC; thus, we aimed to explore miRNAs, which plays an important role in the occurrence and development of GBC.MethodsMicroarray analysis was perform...

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Bibliographic Details
Main Authors: Yiyu Qin, Yongliang Zheng, Cheng Huang, Yuanyuan Li, Min Gu, Qin Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Oncology
Subjects:
gallbladder cancer
miR-181b-5p
hypoxia
viability
pyruvate dehydrogenase complex component X
glycolysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.683725/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.683725/full

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