Tolerability assessment of a lectin fraction from Tepary bean seeds (Phaseolus acutifolius) orally administered to rats

Our previous studies have shown that a lectin rich fraction (TBLF) extracted from Tepary bean seeds differentially inhibits cancer cells proliferation in vitro. Before testing the in vivo anticancer effect, the acute and subchronic toxicological assays in rats were conducted, where an oral dose of 5...

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Main Authors: Roberto Ferriz-Martínez, Karina García-García, Iovanna Torres-Arteaga, Adriana Jheny Rodriguez-Mendez, María de Jesús Guerrero-Carrillo, Ulisses Moreno-Celis, Marco Vinicio Ángeles-Zaragoza, Alejandro Blanco-Labra, Marco Alonso Gallegos-Corona, Juan Pablo Robles-Álvarez, Elizabeth Mendiola-Olaya, Héctor Mario Andrade-Montemayor, Olga Patricia Garcia, Teresa Garcia-Gasca
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014001127