Estimation of low quantity genes: a hierarchical model for analyzing censored quantitative real-time PCR data.

Analysis of gene quantities measured by quantitative real-time PCR (qPCR) can be complicated by observations that are below the limit of quantification (LOQ) of the assay. A hierarchical model estimated using MCMC methods was developed to analyze qPCR data of genes with observations that fall below...

Full description

Bibliographic Details
Main Authors: Tim C Boyer, Tim Hanson, Randall S Singer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23741414/?tool=EBI