Sam68 mediates leptin signaling and action in human granulosa cells: possible role in leptin resistance in PCOS

Introduction: Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, obesity, and insulin resistance, that leads to subfertility. Sam68 is an RNA-binding protein with signaling functions that is ubiquitously expressed, including gona...

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Bibliographic Details
Main Authors: Teresa Vilariño-García, Antonio Pérez-Pérez, Esther Santamaría-López, Nicolás Prados, Manuel Fernández-Sánchez, Víctor Sánchez-Margalet
Format: Article
Language:English
Published: Bioscientifica 2020-06-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/9/6/EC-20-0062.xml