Reformulating Small Molecules for Cardiovascular Disease Immune Intervention: Low-Dose Combined Vitamin D/Dexamethasone Promotes IL-10 Production and Atheroprotection in Dyslipidemic Mice

Reformulating Small Molecules for Cardiovascular Disease Immune Intervention: Low-Dose Combined Vitamin D/Dexamethasone Promotes IL-10 Production and Atheroprotection in Dyslipidemic Mice

The targeting of proinflammatory pathways has a prophylactic and therapeutic potential on atherosclerotic cardiovascular diseases (CVD). An alternative/complementary strategy is the promotion of endogenous atheroprotective mechanisms that are impaired during atherosclerosis progression, such as the...

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Bibliographic Details
Main Authors: Laura Ospina-Quintero, Julio C. Jaramillo, Jorge H. Tabares-Guevara, José R. Ramírez-Pineda
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
atherosclerosis
immune intervention
Vitamin D3
Dexamethasone
interleukin-10
immunoregulatory cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00743/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00743/full

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