Evidences of HEV genotype 3 persistence and reactivity in liver parenchyma from experimentally infected cynomolgus monkeys (Macaca fascicularis).

Hepatitis E virus genotype 3 (HEV-3) is an emerging zoonotic pathogen, responsible for sporadic cases of acute hepatitis E worldwide. Primate models have proven to be an essential tool for the study of HEV pathogenesis. Here we describe the outcomes of HEV infection in Macaca fascicularis (cynomolgu...

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Main Authors: Diana Chaves Pereira Mejido, Jaqueline Mendes de Oliveira, Ana Maria Coimbra Gaspar, Noemi Rovaris Gardinali, Fernanda de Oliveira Bottino, Lilian Gonçalves de Carvalho, Debora Regina Lopes Dos Santos, Yohan Brito Kevorkian, Leandro Layter Xavier, Julio Moran, Marcelo Pelajo-Machado, Renato Sergio Marchevsky, Marcelo Alves Pinto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218472