INPP4B protects from metabolic syndrome and associated disorders

INPP4B protects from metabolic syndrome and associated disorders

Characterizing mice lacking Inositol Polyphosphate-4-Phosphatase Type II B (INPP4B), Zhang et al. discovered that SREBP1 signaling is activated in livers of Inpp4b −/− males leading to development of NAFLD and insulin resistance. When fed high fat diet, Inpp4b −/− males develop type II diabetes, inf...

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Bibliographic Details
Main Authors: Manqi Zhang, Yasemin Ceyhan, Elena M. Kaftanovskaya, Judy L. Vasquez, Jean Vacher, Filip K. Knop, Lubov Nathanson, Alexander I. Agoulnik, Michael M. Ittmann, Irina U. Agoulnik
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01940-6

Internet

https://doi.org/10.1038/s42003-021-01940-6

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