Quantitation of DNA methylation in Epstein-Barr virus–associated nasopharyngeal carcinoma by bisulfite amplicon sequencing

Quantitation of DNA methylation in Epstein-Barr virus–associated nasopharyngeal carcinoma by bisulfite amplicon sequencing

Abstract Background Epigenetic changes, including DNA methylation, disrupt normal cell function, thus contributing to multiple steps of carcinogenesis. Nasopharyngeal carcinoma (NPC) is endemic in southern China and is highly associated with Epstein-Barr virus (EBV) infection. Significant changes of...

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Bibliographic Details
Main Authors: Weilin Zhao, Yingxi Mo, Shumin Wang, Kaoru Midorikawa, Ning Ma, Yusuke Hiraku, Shinji Oikawa, Guangwu Huang, Zhe Zhang, Mariko Murata, Kazuhiko Takeuchi
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Cancer
Subjects:
DNA methylation
Methyl-capture sequencing
Bisulfite amplicon sequencing
Nasopharyngeal carcinoma
Epigenetic mark
Online Access:http://link.springer.com/article/10.1186/s12885-017-3482-3

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http://link.springer.com/article/10.1186/s12885-017-3482-3

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