Defective Generation and Maturation of Dendritic Cells from Monocytes in Colorectal Cancer Patients during the Course of Disease

Colorectal cancer (CRC) is the second-leading cause of cancer-related deaths in Western countries. Today, the role of the host’s immune system in controlling the progression and spread of solid tumors is broadly established. Tumor immunosurveillance escape mechanisms, such as those involving dendrit...

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Bibliographic Details
Main Authors: Rita Consolini, Paolo Miccoli, Alessandra Failli, Paola Ferrari, Andrea Nicolini, Roberto Spisni, Annalisa Legitimo, Giulia Orsini
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/14/11/22022