Mechanisms of Mitochondrial Dysfunction in Lysosomal Storage Disorders: A Review
Mitochondrial dysfunction is emerging as an important contributory factor to the pathophysiology of lysosomal storage disorders (LSDs). The cause of mitochondrial dysfunction in LSDs appears to be multifactorial, although impaired mitophagy and oxidative stress appear to be common inhibitory mechani...
Main Authors: | Karolina M. Stepien, Federico Roncaroli, Nadia Turton, Christian J. Hendriksz, Mark Roberts, Robert A. Heaton, Iain Hargreaves |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-08-01
|
Series: | Journal of Clinical Medicine |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0383/9/8/2596 |
Similar Items
-
Mitochondrial Dysfunction in Lysosomal Storage Disorders
by: Mario de la Mata, et al.
Published: (2016-10-01) -
Potential Treatment of Lysosomal Storage Disease through Modulation of the Mitochondrial–Lysosomal Axis
by: Myeong Uk Kuk, et al.
Published: (2021-02-01) -
Insight into the Role of Extracellular Vesicles in Lysosomal Storage Disorders
by: Brunella Tancini, et al.
Published: (2019-07-01) -
Aminochrome Induces Irreversible Mitochondrial Dysfunction by Inducing Autophagy Dysfunction in Parkinson's Disease
by: Juan Segura-Aguilar, et al.
Published: (2018-03-01) -
The rapidly evolving view of lysosomal storage diseases
by: Giancarlo Parenti, et al.
Published: (2021-02-01)