Coenzyme Q10 and Degenerative Disorders Affecting Longevity: An Overview

by David Mantle, Iain Hargreaves
Published 2019-02-01

Disorders of Human Coenzyme Q10 Metabolism: An Overview

by Iain Hargreaves, Robert A. Heaton, David Mantle
Published 2020-09-01

Blood Mononuclear Cell Mitochondrial Respiratory Chain Complex IV Activity is Decreased in Multiple Sclerosis Patients: Effects of β-Interferon Treatment

by Iain Hargreaves, Nimesh Mody, John Land, Simon Heales
Published 2018-02-01

Oxidative Stress: Mechanistic Insights into Inherited Mitochondrial Disorders and Parkinson’s Disease

by Mesfer Al Shahrani, Simon Heales, Iain Hargreaves, Michael Orford
Published 2017-10-01

The Effect of Cellular Coenzyme Q₁₀ Deficiency on Lysosomal Acidification

by Robert. A. Heaton, Simon Heales, Khalid Rahman, Darren. W. Sexton, Iain Hargreaves
Published 2020-06-01

Measurement of Respiratory Chain Enzyme Activity in Human Renal Biopsy Specimens

by Arun Ghose, Christopher M. Taylor, Alexander J. Howie, Anapurna Chalasani, Iain Hargreaves, David V. Milford
Published 2017-09-01

Mechanisms of Mitochondrial Dysfunction in Lysosomal Storage Disorders: A Review

by Karolina M. Stepien, Federico Roncaroli, Nadia Turton, Christian J. Hendriksz, Mark Roberts, Robert A. Heaton, Iain Hargreaves
Published 2020-08-01

Coenzyme Q10 Levels Are Decreased in the Cerebellum of Multiple-System Atrophy Patients.

by Lucia V Schottlaender, Conceição Bettencourt, Aoife P Kiely, Annapurna Chalasani, Viruna Neergheen, Janice L Holton, Iain Hargreaves, Henry Houlden
Published 2016-01-01

Role of Coenzyme Q₁₀ in Health and Disease: An Update on the Last 10 Years (2010–2020)

by Ilenia Cirilli, Elisabetta Damiani, Phiwayinkosi Vusi Dludla, Iain Hargreaves, Fabio Marcheggiani, Lauren Elizabeth Millichap, Patrick Orlando, Sonia Silvestri, Luca Tiano
Published 2021-08-01

Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration

by Kira M. Holmström, Liam Baird, Ying Zhang, Iain Hargreaves, Annapurna Chalasani, John M. Land, Lee Stanyer, Masayuki Yamamoto, Albena T. Dinkova-Kostova, Andrey Y. Abramov
Published 2013-06-01

Coenzyme Q in the Treatment of Mitochondrial Disease

by Viruna Neergheen MSc, Annapurna Chalasani MSc, Luke Wainwright MSci, MRes, Delia Yubero PhD, Raquel Montero PhD, Rafael Artuch MD, PhD, Iain Hargreaves PhD
Published 2017-05-01

Ammonium tetrathiomolybdate following ischemia/reperfusion injury: Chemistry, pharmacology, and impact of a new class of sulfide donor in preclinical injury models.

by Alex Dyson, Felipe Dal-Pizzol, Giovanni Sabbatini, Anna B Lach, Federica Galfo, Juliano Dos Santos Cardoso, Bruna Pescador Mendonça, Iain Hargreaves, Bernardo Bollen Pinto, Daniel I Bromage, John F Martin, Kevin P Moore, Martin Feelisch, Mervyn Singer
Published 2017-07-01

NDUFA4 Mutations Underlie Dysfunction of a Cytochrome c Oxidase Subunit Linked to Human Neurological Disease

by Robert D.S. Pitceathly, Shamima Rahman, Yehani Wedatilake, James M. Polke, Sebahattin Cirak, A. Reghan Foley, Anna Sailer, Matthew E. Hurles, Jim Stalker, Iain Hargreaves, Cathy E. Woodward, Mary G. Sweeney, Francesco Muntoni, Henry Houlden, Jan-Willem Taanman, Michael G. Hanna
Published 2013-07-01

NDUFA4 Mutations Underlie Dysfunction of a Cytochrome c Oxidase Subunit Linked to Human Neurological Disease

by Robert D.S. Pitceathly, Shamima Rahman, Yehani Wedatilake, James M. Polke, Sebahattin Cirak, A. Reghan Foley, Anna Sailer, Matthew E. Hurles, Jim Stalker, Iain Hargreaves, Cathy E. Woodward, Mary G. Sweeney, Francesco Muntoni, Henry Houlden, Jan-Willem Taanman, Michael G. Hanna
Published 2013-06-01

Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

by Alison Wood-Kaczmar, Sonia Gandhi, Zhi Yao, Andrey Y. Abramov, Erik A. Miljan, Gregory Keen, Lee Stanyer, Iain Hargreaves, Kristina Klupsch, Emma Deas, Julian Downward, Louise Mansfield, Parmjit Jat, Joanne Taylor, Simon Heales, Michael R. Duchen, David Latchman, Sarah J. Tabrizi, Nicholas W. Wood
Published 2008-01-01

Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

by Alison Wood-Kaczmar, Sonia Gandhi, Zhi Yao, Andrey Y. Abramov, Erik A. Miljan, Gregory Keen, Lee Stanyer, Iain Hargreaves, Kristina Klupsch, Emma Deas, Julian Downward, Louise Mansfield, Parmjit Jat, Joanne Taylor, Simon Heales, Michael R. Duchen, David Latchman, Sarah J. Tabrizi, Nicholas W. Wood
Published 2008-01-01

Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons.

by Alison Wood-Kaczmar, Sonia Gandhi, Zhi Yao, Andrey Y. Abramov, Erik A. Miljan, Gregory Keen, Lee Stanyer, Iain Hargreaves, Kristina Klupsch, Emma Deas, Julian Downward, Louise Mansfield, Parmjit Jat, Joanne Taylor, Simon Heales, Michael R. Duchen, David Latchman, Sarah J. Tabrizi, Nicholas W. Wood
Published 2008-01-01

PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons.

by Alison Wood-Kaczmar, Sonia Gandhi, Zhi Yao, Andrey Y Abramov, Erik A Miljan, Gregory Keen, Lee Stanyer, Iain Hargreaves, Kristina Klupsch, Emma Deas, Julian Downward, Louise Mansfield, Parmjit Jat, Joanne Taylor, Simon Heales, Michael R Duchen, David Latchman, Sarah J Tabrizi, Nicholas W Wood
Published 2008-06-01

Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons.

by Alison Wood-Kaczmar, Sonia Gandhi, Zhi Yao, Andrey Y. Abramov, Erik A. Miljan, Gregory Keen, Lee Stanyer, Iain Hargreaves, Kristina Klupsch, Emma Deas, Julian Downward, Louise Mansfield, Parmjit Jat, Joanne Taylor, Simon Heales, Michael R. Duchen, David Latchman, Sarah J. Tabrizi, Nicholas W. Wood
Published 2008-01-01

A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy.

by Houman Ashrafian, Louise Docherty, Vincenzo Leo, Christopher Towlson, Monica Neilan, Violetta Steeples, Craig A Lygate, Tertius Hough, Stuart Townsend, Debbie Williams, Sara Wells, Dominic Norris, Sarah Glyn-Jones, John Land, Ivana Barbaric, Zuzanne Lalanne, Paul Denny, Dorota Szumska, Shoumo Bhattacharya, Julian L Griffin, Iain Hargreaves, Narcis Fernandez-Fuentes, Michael Cheeseman, Hugh Watkins, T Neil Dear
Published 2010-06-01