The Tug1 lncRNA locus is essential for male fertility

The Tug1 lncRNA locus is essential for male fertility

Abstract Background Several long noncoding RNAs (lncRNAs) have been shown to function as components of molecular machines that play fundamental roles in biology. While the number of annotated lncRNAs in mammalian genomes has greatly expanded, studying lncRNA function has been a challenge due to thei...

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Bibliographic Details
Main Authors: Jordan P. Lewandowski, Gabrijela Dumbović, Audrey R. Watson, Taeyoung Hwang, Emily Jacobs-Palmer, Nydia Chang, Christian Much, Kyle M. Turner, Christopher Kirby, Nimrod D. Rubinstein, Abigail F. Groff, Steve C. Liapis, Chiara Gerhardinger, Assaf Bester, Pier Paolo Pandolfi, John G. Clohessy, Hopi E. Hoekstra, Martin Sauvageau, John L. Rinn
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Genome Biology
Subjects:
Tug1
lncRNA
Fertility
DNA repressor
Cis-regulatory elements
RNA-seq
Online Access:http://link.springer.com/article/10.1186/s13059-020-02081-5

Internet

http://link.springer.com/article/10.1186/s13059-020-02081-5

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