Impact of IFN-Free and IFN-Based Treatment on Blood Myeloid Dendritic Cell, Monocyte, Slan-DC, and Activated T Lymphocyte Dynamics during HCV Infection

Chronic hepatitis C virus infection leads to the activation of innate immunity, a key component in HCV fibrosis. In the past, the use of IFN-based treatment regimens did not permit an adequate evaluation of the impact of HCV clearance on immune cells, because of their antiviral and immunomodulatory...

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Main Authors: Serena Vita, Paola Zuccalà, Stefano Savinelli, Claudia Mascia, Raffaella Rossi, Francesco Schiavone, Raffaella Marocco, Tiziana Tieghi, Marco Iannetta, Parni Nijhawan, Maria Antonella Zingaropoli, Gabriella d’Ettore, Vincenzo Vullo, Claudio Maria Mastroianni, Miriam Lichtner
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2020/2781350