Efficacy of Periconceptional High-Dose Folic Acid in Isolated Orofacial Cleft Prevention: A Systematic Review

Background The effectiveness of folic acid in prevention of neural tube defects has been well established. Periconceptional supplementation of folic acid in low doses has been shown to be effective in some studies on its efficacy in prevention of occurrence of clefts. There are few studies on high-d...

Full description

Bibliographic Details
Main Authors: Rajshree Jayarajan, Anantharajan Natarajan, Ravindranathan Nagamuttu
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2019-05-01
Series:Indian Journal of Plastic Surgery
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1696864