The Neuroprotective Effect of Liraglutide is Mediated by Glucagon-Like Peptide 1 Receptor-Mediated Activation of cAMP/PKA/CREB Pathway

The Neuroprotective Effect of Liraglutide is Mediated by Glucagon-Like Peptide 1 Receptor-Mediated Activation of cAMP/PKA/CREB Pathway

Background/Aims: Glucagon-like peptide-1 (GLP-1)-based drugs are being used to achieve better glucose control in patients with type 2 diabetes, and GLP-1 mimetics such as liraglutide have shown therapeutic potential in preventing diabetes-related microvascular and macrovascular complications as well...

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Bibliographic Details
Main Authors: Yi Bao, Lei Jiang, Haiyan Chen, Junjie Zou, Zhimin Liu, Yongquan Shi
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Liraglutide
AGEs
Astrocytes
cAMP
GLP-1
Online Access:http://www.karger.com/Article/FullText/430199

Internet

http://www.karger.com/Article/FullText/430199

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