A mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress

A mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress

Renal fibrosis is a common feature of renal failure resulting from multiple etiologies, including diabetic nephropathy, hypertension and inherited renal disorders. However, the mechanisms of renal fibrosis are incompletely understood and we therefore explored these by establishing a mouse model for...

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Bibliographic Details
Main Authors: Sian E. Piret, Eric Olinger, Anita A. C. Reed, M. Andrew Nesbit, Tertius A. Hough, Liz Bentley, Olivier Devuyst, Roger D. Cox, Rajesh V. Thakker
Format: Article
Language:English
Published: The Company of Biologists 2017-06-01
Series:Disease Models & Mechanisms
Subjects:
Kidney
Fibrosis
ER stress
Mouse model
Endoplasmic reticulum
Online Access:http://dmm.biologists.org/content/10/6/773

Internet

http://dmm.biologists.org/content/10/6/773

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