Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling

Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling

Summary: Alternative splicing is well understood to enhance proteome diversity as cells respond to stimuli. However, mechanistic understanding for how the spliceosome processes precursor messenger RNA (mRNA) transcripts to achieve template diversification is incomplete. We use recently developed enz...

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Bibliographic Details
Main Authors: Patrick J. Metz, Keith A. Ching, Tao Xie, Paulina Delgado Cuenca, Sherry Niessen, John H. Tatlock, Kristen Jensen-Pergakes, Brion W. Murray
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720300796

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http://www.sciencedirect.com/science/article/pii/S2211124720300796

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