Cell fate reprogramming by control of intracellular network dynamics.

Identifying control strategies for biological networks is paramount for practical applications that involve reprogramming a cell's fate, such as disease therapeutics and stem cell reprogramming. Here we develop a novel network control framework that integrates the structural and functional info...

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Bibliographic Details
Main Authors: Jorge G T Zañudo, Réka Albert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4388852?pdf=render