Functional characterization of a bioengineered liver after heterotopic implantation in pigs

Anderson et al. demonstrate a method for seeding and engrafting primary porcine hepatocytes into a bioengineered liver (BEL) scaffold previously reendothelialized with HUVECs. This study constitutes an important advance in the effort to generate transplantable livers of a clinically relevant size fo...

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Bibliographic Details
Main Authors: Brett D. Anderson, Erek D. Nelson, DongJin Joo, Bruce P. Amiot, Aleksandr A. Katane, Alyssa Mendenhall, Benjamin G. Steiner, Aron R. Stumbras, Victoria L. Nelson, R. Noelle Palumbo, Thomas W. Gilbert, Dominique S. Davidow, Jeffrey J. Ross, Scott L. Nyberg
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02665-2