Hyaluronate fragments reverse skin atrophy by a CD44-dependent mechanism.

BACKGROUND: Skin atrophy is a common manifestation of aging and is frequently accompanied by ulceration and delayed wound healing. With an increasingly aging patient population, management of skin atrophy is becoming a major challenge in the clinic, particularly in light of the fact that there are n...

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Bibliographic Details
Main Authors: Gürkan Kaya, Christian Tran, Olivier Sorg, Raymonde Hotz, Denise Grand, Pierre Carraux, Liliane Didierjean, Ivan Stamenkovic, Jean-Hilaire Saurat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1702558?pdf=render