Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers.

Understanding the formation mechanism of lipid nanoparticles in microfluidic devices with chaotic micromixers.

Lipid nanoparticles (LNPs) or liposomes are the most widely used drug carriers for nanomedicines. The size of LNPs is one of the essential factors affecting drug delivery efficiency and therapeutic efficiency. Here, we demonstrated the effect of lipid concentration and mixing performance on the LNP...

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Bibliographic Details
Main Authors: Masatoshi Maeki, Yuka Fujishima, Yusuke Sato, Takao Yasui, Noritada Kaji, Akihiko Ishida, Hirofumi Tani, Yoshinobu Baba, Hideyoshi Harashima, Manabu Tokeshi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5705116?pdf=render

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http://europepmc.org/articles/PMC5705116?pdf=render

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