Activation of nicotinic cholinergic receptors prevents ventilator-induced lung injury in rats.

Respiratory distress syndrome is responsible for 40 to 60 percent mortality. An over mortality of about 10 percent could result from additional lung injury and inflammation due to the life-support mechanical ventilation, which stretches the lung. It has been recently demonstrated, in vitro, that pha...

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Bibliographic Details
Main Authors: Fabienne Brégeon, Francois Xeridat, Nicolas Andreotti, Hubert Lepidi, Stéphane Delpierre, Antoine Roch, Sylvie Ravailhe, Yves Jammes, Jean-Guillaume Steinberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3152549?pdf=render