CYP17 inhibitors in prostate cancer: latest evidence and clinical potential

Since androgen signaling plays a pivotal role in the proliferation and metastasis of prostate cancer, androgen deprivation therapy (ADT) or castration therapy is considered the backbone of treatment for newly diagnosed metastatic prostate cancer. However, almost all men experience disease progressio...

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Bibliographic Details
Main Authors: Anitha B. Alex, Sumanta K. Pal, Neeraj Agarwal
Format: Article
Language:English
Published: SAGE Publishing 2016-07-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/1758834016642370