Validation of cross-genotype neutralization by hepatitis B virus-specific monoclonal antibodies by in vitro and in vivo infection.

Vaccines based on hepatitis B virus (HBV) genotype A have been used worldwide for immunoprophylaxis and are thought to prevent infections by non-A HBV strains effectively, whereas, vaccines generated from genotype C have been used in several Asian countries, including Japan and Korea, where HBV geno...

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Main Authors: Susumu Hamada-Tsutsumi, Etsuko Iio, Tsunamasa Watanabe, Shuko Murakami, Masanori Isogawa, Sayuki Iijima, Takako Inoue, Kayoko Matsunami, Kazuto Tajiri, Tatsuhiko Ozawa, Hiroyuki Kishi, Atsushi Muraguchi, Takashi Joh, Yasuhito Tanaka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4333126?pdf=render