Gadolinium Tagged Osteoprotegerin-Mimicking Peptide: A Novel Magnetic Resonance Imaging Biospecific Contrast Agent for the Inhibition of Osteoclastogenesis and Osteoclast Activity

Gadolinium Tagged Osteoprotegerin-Mimicking Peptide: A Novel Magnetic Resonance Imaging Biospecific Contrast Agent for the Inhibition of Osteoclastogenesis and Osteoclast Activity

The control of osteoblast/osteoclast cross-talk is crucial in the bone remodelling process and provides a target mechanism in the development of drugs for bone metabolic diseases. Osteoprotegerin is a key molecule in this biosignalling pathway as it inhibits osteoclastogenesis and osteoclast activat...

Full description

Bibliographic Details
Main Authors: Lubinda Mbundi, Steve T. Meikle, Rosa Busquets, Nicholas G. Dowell, Mara Cercignani, Matteo Santin
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Nanomaterials
Subjects:
osteoclastogenesis
RANK-RANKL-OPG
mimetic peptide
Gadolinium chelate
MRI
Online Access:http://www.mdpi.com/2079-4991/8/6/399

Internet

http://www.mdpi.com/2079-4991/8/6/399

Similar Items