Aberrant Methylation of LINE-1 Transposable Elements: A Search for Cancer Biomarkers

Cancer remains one of the main causes of human mortality despite significant progress in its diagnostics and therapy achieved in the past decade. Massive hypomethylation of retrotransposons, in particular LINE-1, is considered a hallmark of most malignant transformations as it results in the reactiv...

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Bibliographic Details
Main Authors: Anastasia A. Ponomaryova, Elena Y. Rykova, Polina A. Gervas, Nadezhda V. Cherdyntseva, Ilgar Z. Mamedov, Tatyana L. Azhikina
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/9/2017