High resolution respirometry to assess function of mitochondria in native homogenates of human heart muscle.

Impaired myocardial bioenergetics is a hallmark of many cardiac diseases. There is a need of a simple and reproducible method of assessment of mitochondrial function from small human myocardial tissue samples. In this study we adopted high-resolution respirometry to homogenates of fresh human cardia...

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Bibliographic Details
Main Authors: Adéla Krajčová, Tomáš Urban, David Megvinet, Petr Waldauf, Martin Balík, Jan Hlavička, Petr Budera, Libor Janoušek, Eva Pokorná, František Duška
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226142