An increase in mitochondrial DNA promotes nuclear DNA replication in yeast.
Coordination between cellular metabolism and DNA replication determines when cells initiate division. It has been assumed that metabolism only plays a permissive role in cell division. While blocking metabolism arrests cell division, it is not known whether an up-regulation of metabolic reactions ac...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-04-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2289842?pdf=render |