Bepridil Facilitates Early Termination of Spiral-Wave Reentry in Two-Dimensional Cardiac Muscle Through an Increase of Intercellular Electrical Coupling

Bepridil Facilitates Early Termination of Spiral-Wave Reentry in Two-Dimensional Cardiac Muscle Through an Increase of Intercellular Electrical Coupling

Bepridil is effective for conversion of atrial fibrillation to sinus rhythm and in the treatment of drug-refractory ventricular tachyarrhythmias. We investigated the effects of bepridil on electrophysiological properties and spiral-wave (SW) reentry in a 2-dimensional ventricular muscle layer of iso...

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Bibliographic Details
Main Authors: Hiroki Takanari, Haruo Honjo, Yoshio Takemoto, Tomoyuki Suzuki, Sara Kato, Masahide Harada, Yusuke Okuno, Takashi Ashihara, Tobias Opthof, Ichiro Sakuma, Kaichiro Kamiya, Itsuo Kodama
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319307959

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http://www.sciencedirect.com/science/article/pii/S1347861319307959

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