The Inhibition of Phosphoinositide-3 Kinases Induce Resolution of Inflammation in a Gout Model

The Inhibition of Phosphoinositide-3 Kinases Induce Resolution of Inflammation in a Gout Model

Phosphoinositide-3 kinases (PI3Ks) are central signaling enzymes that are involved in many aspects of immune cell function. PI3Kγ and PI3Kδ are the major isoforms expressed in leukocytes. The role of PI3K isoforms in the resolution of inflammation is still poorly understood. Here, we investigated th...

Full description

Bibliographic Details
Main Authors: Izabela Galvão, Celso Martins Queiroz-Junior, Vivian Louise Soares de Oliveira, Vanessa Pinho, Emilio Hirsch, Mauro Martins Teixeira
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
gout
neutrophil
resolution of inflammation
phosphoinositide-3 kinases
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01505/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01505/full

Similar Items