Development of AAVLP(HPV16/31L2) particles as broadly protective HPV vaccine candidate.

Development of AAVLP(HPV16/31L2) particles as broadly protective HPV vaccine candidate.

The human papillomavirus (HPV) minor capsid protein L2 is a promising candidate for a broadly protective HPV vaccine yet the titers obtained in most experimental systems are rather low. Here we examine the potential of empty AAV2 particles (AAVLPs), assembled from VP3 alone, for display of L2 epitop...

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Bibliographic Details
Main Authors: Karen Nieto, Margit Weghofer, Peter Sehr, Mirko Ritter, Sebastian Sedlmeier, Balasubramanyam Karanam, Hanna Seitz, Martin Müller, Markus Kellner, Markus Hörer, Uwe Michaelis, Richard B S Roden, Lutz Gissmann, Jürgen A Kleinschmidt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3384601?pdf=render

Internet

http://europepmc.org/articles/PMC3384601?pdf=render

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