Combination proximal pulmonary artery coiling and distal embolization induces chronic elevations in pulmonary artery pressure in Swine.

Combination proximal pulmonary artery coiling and distal embolization induces chronic elevations in pulmonary artery pressure in Swine.

Pulmonary hypertension (PH) is associated with aberrant vascular remodeling and right ventricular (RV) dysfunction that contribute to early mortality. Large animal models that recapitulate human PH are essential for mechanistic studies and evaluating novel therapies; however, these models are not re...

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Bibliographic Details
Main Authors: Jaume Aguero, Kiyotake Ishikawa, Kenneth M Fish, Nadjib Hammoudi, Lahouaria Hadri, Ana Garcia-Alvarez, Borja Ibanez, Valentin Fuster, Roger J Hajjar, Jane A Leopold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4414513?pdf=render

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http://europepmc.org/articles/PMC4414513?pdf=render

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