Electroacupuncture prevents cocaine-induced conditioned place preference reinstatement and attenuates ΔFosB and GluR2 expression

Abstract Acupuncture has been used for treating drug addiction since the 1970s, but little is known about the mechanisms by which acupuncture affects drug cue-induced relapse. The transcription factor delta-FosB (ΔFosB) plays a critical role in behavior and pathology after chronic use of cocaine. ΔF...

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Bibliographic Details
Main Authors: Ai T. M. Nguyen, Tran V. B. Quach, Peddanna Kotha, Szu-Yu Chien, Iona J. MacDonald, Hsien-Yuan Lane, Cheng-Hao Tu, Jaung-Geng Lin, Yi-Hung Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93014-0