Ubiquitination is involved in secondary growth, not initial formation of polyglutamine protein aggregates in <it>C. elegans</it>

<p>Abstract</p> <p>Background</p> <p>Protein misfolding and subsequent aggregation are hallmarks of several human diseases. The cell has a variety of mechanisms for coping with misfolded protein stress, including ubiquitin-mediated protein degradation. In fact, the pres...

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Bibliographic Details
Main Authors: Skibinski Gregory A, Boyd Lynn
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/13/10