microRNA-150 regulates mobilization and migration of bone marrow-derived mononuclear cells by targeting Cxcr4.

The interaction between chemokine receptor type 4 (CXCR4) and its ligand, stromal cell-derived factor (SDF)-1, plays an important role in stem cell mobilization and migration in ischemic tissues. MicroRNAs (miRs) are key regulators of stem cell function and are involved in regulation of stem cell su...

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Bibliographic Details
Main Authors: Nobuko Tano, Ha Won Kim, Muhammad Ashraf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3198444?pdf=render