Assessment of Pharmacogenomic Panel Assay for Prediction of Taxane Toxicities: Preliminary Results

Assessment of Pharmacogenomic Panel Assay for Prediction of Taxane Toxicities: Preliminary Results

Backbone: Paclitaxel and docetaxel are the primary taxane anticancer drugs regularly used to treat, breast, gastric, ovarian, head/neck, lung, and genitourinary neoplasm. Suspension of taxane treatments compromising patient benefits is more frequently caused by peripheral neuropathy and allergy, tha...

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Bibliographic Details
Main Authors: Raffaele Di Francia, Luigi Atripaldi, Salvo Di Martino, Carla Fierro, Tommaso Muto, Anna Crispo, Sabrina Rossetti, Gaetano Facchini, Massimiliano Berretta
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Pharmacology
Subjects:
genotyping methods
ABCB1
ABCG2
CYP3A4*1B
CYP2C8*3
ERCC2
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00797/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00797/full

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