Sphingosylphosphorylcholine is an activator of transglutaminase activity in human keratinocytes

We characterize functional roles of a newly discovered chemical, sphingosylphosphorylcholine (SPC), in the epidermis by elucidating the biological effect of SPC on human keratinocytes in culture. The intracellular calcium level of human keratinocytes was increased by incubation with SPC, but not wit...

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Bibliographic Details
Main Authors: Kazuhiko Higuchi, Makoto Kawashima, Yutaka Takagi, Hidehiko Kondo, Yukihiro Yada, Yoshiaki Ichikawa, Genji Imokawa
Format: Article
Language:English
Published: Elsevier 2001-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520322094