A Luminex assay detects amyloid β oligomers in Alzheimer's disease cerebrospinal fluid.

Amyloid beta (aβ) protein assembles into larger protein aggregates during the pathogenesis of Alzheimer's disease (AD) and there is increasing evidence that soluble aβ oligomers are a critical pathologic species. Diagnostic evaluations rely on the measurement of increased tau and decreased aβ42...

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Bibliographic Details
Main Authors: Adrianna Z Herskovits, Joseph J Locascio, Elaine R Peskind, Ge Li, Bradley T Hyman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23844122/?tool=EBI